6-keto PGF1alpha EIA Kit

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Description Size Catalog# Price Quantity  
6-keto PGF1alpha EIA Kit  1x96 well 900-004 $320.00  
6-keto PGF1alpha EIA Kit  5x96 well 901-004 $1,275.00  
Background
6-keto-PGF1alpha is a stable hydrolysis product of prostacyclin (PGI2). Due to the short half-life of PGI2 in buffer (2-3 minutes) the production of prostacyclin is typically monitored by measurement of the 6-keto-PGF1alpha metabolite and its derivative in urine, 2,3-dinor-6-keto-PGF1alpha. PGI2 has autocoid functions that include platelet aggregation, inhibition of vasoconstrictor responses to pressor hormones, platelet anti- and disaggregatory properties, and reproductive functions. The effects are induced by receptor-mediated elevation of cAMP. Prostacyclin has clinical applications in atherosclerosis and protection from myocardial ischemia.

Normalize urine samples to creatinine with our Creatinine Colorimetric Detection Kit.

Table of Abbreviations

Abbreviated Name
6-keto PGF1alpha EIA Kit

Applications
EIA

Features

  • Results in just 3 hours
  • Convenient 4°C storage
  • Validated in multiple same matrices

Range
3.2 - 50,000 pg/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
6-keto-PGF1alpha 100%
2.3-dinor-6-keto-PGF1alpha 3.17%
PGF2alpha 1.67%
PGD2 0.60%
PGF1alpha 0.60%
PGE1 0.20%
6.15-diketo-13,14-dihydro-PGF1alpha 0.12%
<0.01%: 13,14-dihydro-15-keto-PGF1alpha, 15-keto-PGF2alpha, PGA2, PGB1, PGE2, Thromboxane B2, 15-Hp-HETE, 2-Arachidonoylglycerol, Anandamide

Sample Types
culture media, saliva, urine, serum

Samples Per Kit
38 in duplicate per 96 well kit

Sensitivity
1.40 pg/mL

Species Reactivity
Species Independent

Time To Answer
< 3 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
AssayLayout

Product Manual

Product Name Catalog # Manual
6-keto PGF1alpha EIA Kit 900-004   Kit Insert    MSDS   
6-keto PGF1alpha EIA Kit 901-004   Kit Insert    MSDS   

Ordering Info
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