PGE2 EIA Kit

Brand: Assay Designs

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Description	Size	Catalog#	Price	Quantity
PGE2 EIA Kit	1x96 well	900-001	$310.00
PGE2 EIA Kit	5x96 well	901-001	$1,240.00

Background

Prostaglandin E2 (PGE2) is an extensively studied prostaglandin owing to its predominance in inflammation, cancer, atherosclerosis, autoimmune disease, and sepsis. Oxidation of arachidonic acid by prostaglandin synthases (COX-1 and COX-2) produces prostaglandin H2 (PGH2), which is further metabolized by PGE synthases into its major product, PGE2. PGE2 mediates autocrine and paracrine signaling by binding to G-protein coupled receptors (EP1, EP2, EP3, EP4) on the cell surface, functioning to modulate phospholipase C and adenylate cyclase activity. PGE2 has been of great interest as a therapeutic target, either by modulation of its synthesis by COX inhibitors (NSAIDS) or by modulation of its receptors by downregulation or binding antagonists. PGE2 production in a variety of tissues has been shown to modulate numerous physiological processes including natriuresis in the kidney, smooth muscle elasticity in the vasculature, and the inflammatory response to damaged tissues by monocytes and macrophages.

Normalize urine samples to creatinine with our Creatinine Colorimetric Detection Kit.

Table of Abbreviations

Applications
EIA

Features

Highly cited in peer reviewed literature

Range
39.1 - 2,500 pg/mL

Sample Size
100 無

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Cross Reactivities
PGE2 (100%) / PGE1 (70.0%) / PGE3 (16.3%) / PGF1a (1.40%) / PGF2a (0.70%) / 6-keto-PGF1a (0.60%) / PGA2 (0.10%) / PGB1 (0.10%)... <0.10%: 13,14-dihydro-15-keto-PGF2a / 6,15-keto-13,14-dihydro-PGF1a / TXB2 / 2-Arachidonoylyglycerol / Anandamide / PGD2 / Arachidonic Acid

Sample Types
culture media, saliva, serum, urine, whole blood

Samples Per Kit
37 in duplicate per 96 well kit

Sensitivity
13.4 pg/mL

Species Reactivity
Species Independent

Time To Answer
< 3 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
AssayLayout

Product Manual

Product Name	Catalog #	Manual
PGE2 EIA Kit	900-001	Kit Insert MSDS
PGE2 EIA Kit	901-001	Kit Insert MSDS

Related Products

Product Name	Catalog#
11-dehydro-TXB2 EIA Kit	900-092
6-keto PGF1alpha EIA Kit	900-004
COX Activity Kit	907-003
Chromogranin A Recombinant Human Protein	908-252
Creatinine Colorimetric Detection Kit	907-030
Cysteinyl Leukotriene EIA Kit	900-070
Interleukin-10 (mouse) EIA Kit	900-148
Interleukin-1beta (human) EIA Kit	900-130
Interleukin-1beta (mouse) EIA Kit	900-132
Interleukin-1beta (rat) EIA Kit	900-131
PGE1 EIA Kit	900-005
PGE1 EIA Kit	901-005
PGE2 CLIA Kit	910-001
PGE2 FPIA Kit	920-001
PGE2 High Sensitivity EIA Kit	930-001
PGE2 High Sensitivity EIA Kit	931-001
PGE2 Monoclonal Antibody (BG8)	905-628
TGF-beta1 EIA Kit	900-155
TXB2 EIA Kit	900-002
TXB2 EIA Kit	901-002
sPLA2 Activity Kit	907-002

Citations
Launch Citation Database

Ordering Info
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Order by fax: 734-669-0134

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PGE2 EIA Kit