15-deoxy-delta12,14-PGJ2 EIA Kit

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Description Size Catalog# Price Quantity  
15-deoxy-delta12,14-PGJ2 EIA Kit  1x96 well 900-023 $360.00  
15-deoxy-delta12,14-PGJ2 EIA Kit  5x96 well 901-023 $1,440.00  
Background
15-deoxy-Delta12,14-Prostaglandin J2 (15-d-PGJ2) is one of the ultimate dehydration products of PGD2, formed via the intermediate Delta12-PGJ2. 15-d-PGJ2 is physiologically present in body fluids at concentration of 10-12 to 10-9 M, but increases dramatically under stress such as infection and inflammation. 15-d-PGJ2 exerts both pro- and anti-inflammatory effects in a cell-type and concentration-dependent manner, with many of these effects mediated via binding to the gamma isoform of the peroxisome proliferators-activated receptor (PPAR-gamma). 15-d-PGJ2 appears to induce HO-1 expression by a PPAR-gamma-independent mechanism mediated by the generation of reactive oxygen species (ROS).

Table of Abbreviations

Applications
EIA

Features

  • Only 15d-PGJ2 immunoassay kit on the market
  • Much easier than GC/MS

Range
195 - 200,000 pg/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
15-deoxy-Delta12,14-PGJ2 100%
PGJ2 49.2%
Delta12-PGJ2 5.99%
PGD2 4.92%
Arachidonic Acid 0.03%
<0.01%: PGF2alpha / 9alpha,11beta-PGF2alpha / PGE2 / Thromboxane B2 / 2-Arachidonoylglycerol / Anandamide

Sample Types
culture media, saliva, urine, plasma

Samples Per Kit
38 in duplicate per 96 well kit

Sensitivity
36.8 pg/mL

Species Reactivity
Species Independent

Time To Answer
5 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
AssayLayout

Product Manual

Product Name Catalog # Manual
15-deoxy-delta12,14-PGJ2 EIA Kit 900-023   Kit Insert    MSDS   
15-deoxy-delta12,14-PGJ2 EIA Kit 901-023   Kit Insert    MSDS   

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Citations
Launch Citation Database

Ordering Info
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