Arg8-Vasopressin EIA Kit

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Description Size Catalog# Price Quantity  
Arg8-Vasopressin EIA Kit  1x96 well 900-017 $355.00  
Arg8-Vasopressin EIA Kit  5x96 well 901-017 $1,435.00  
Background
Arginine vasopressin (AVP) is a nonapeptide hormone produced in magnocellular neurons of the hypothalamus, which functions as an antidiuretic in the kidney and systemically as a regulator of vasoconstriction, blood volume, and blood pressure. AVP acts by binding to a set of specific seven transmembrane domain-containing G-protein coupled receptors (GPCR) classified into three groups: V1a (V1), V1b (V3), and V2. V1b receptors stimulate adrenocorticotropic hormone (ACTH) release in the anterior pituitary, but may also participate in corticotropin-releasing hormone (CRH) release by the hypothalamus. The V1b receptor signals through coupling of Gq/11 alpha subunits, activating phospholipase C and release of intracellular Ca2+ via phosphoinositide second messengers. V1b receptor overexpression is a common marker for ACTH-secreting corticotropic adenomas. V2 receptors in the collecting ducts of the kidneys stimulate adenylyl cyclase activity, regulating the reabsorption of water via aquaporin channels.

Table of Abbreviations

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Arg8 vasopressin

Features

  • Only Arg8-Vasopressin immunoassay on the market
  • Validated in a number of matrices
  • Highly cited in peer reviewed literature

Applications
EIA

Range
4.10 - 1,000 pg/mL

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Sample Size
100 µL

Cross Reactivities
Arg8-Vasopressin 100%
Lys8-Vasopressin 7.30%

Sample Types
culture media

Samples Per Kit
37 in duplicate per 96 well kit

Sensitivity
3.39 pg/mL

Species Reactivity
Species Independent

Time To Answer
overnight

For research use only, not for diagnostic or therapeutic use.

Documentation
AssayLayout

Product Manual

Product Name Catalog # Manual
Arg8-Vasopressin EIA Kit 900-017   Kit Insert    MSDS   
Arg8-Vasopressin EIA Kit 901-017   Kit Insert    MSDS   

Ordering Info
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