Tunicamycin, N-linked glycosylation Inhibitor

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Description Size Catalog# Price Quantity  
Tunicamycin, N-linked glycosylation Inhibitor 10 mg  908-297 $85.00
Background
Tunicamycin is an inhibitor of the UDP-N-acetylglucosamine-dolichol phosphate N-acetylglucosamine-1-phosphate transferase (GPT), acting to block the initial step of dolichol-linked oligosaccharide biosynthesis. Treatment with tunicamycin blocks the synthesis of asparagine (N)-linked glycoproteins in the ER, and induces expression of binding protein (BiP) as part of the unfolded protein response (UPR).

Table of Abbreviations

Abbreviated Name
Tunicamycin, N-linked glycosylation Inhibitor

Species Reactivity
Species Independent

Applications
Inhibits glycosylation & cell cycle; Induces UPR

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

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