BMP4 Monoclonal Antibody (26H16)

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Description Size Catalog# Price Quantity  
BMP4 Monoclonal Antibody (26H16) 100 µg  905-757-100 $295.00
Background
Bone morphogenic protein 4 (BMP4) is a member of the TGF-beta superfamily that plays a critical role in mammalian mesenchymal development, influencing hematopoeisis and osteoblast differentiation and function. BMP-4 is secreted as 54 kDa inactive precursor peptides that dimerize and are activated following cleavage by members of the proprotein convertase family. Active BMP-4 binds type I and type II serine/threonine kinase receptors which signal via phosphorylation of Smad family proteins. BMP-4 and the highly homologous BMP-2 are functional orthologues of the decapentaplegic (dpp) gene in Drosophila that regulates embryonic leg and wing imaginal disc patterning and larval gut development.

Table of Abbreviations

Abbreviated Name
BMP4 mAb (26H16)

Conjugate

Applications
WB

Isotype
not available

Product Image(s): click to enlarge

Purification
Protein A Affinity

Species Reactivity
H

Immunogen
Recombinant full-length human BMP4 expressed in CHO cells

Host
Mouse

Clone Number
26H16

Positive Control
MKN-48 cell lysates

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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