BMI-1 Polyclonal Antibody

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Description Size Catalog# Price Quantity  
BMI-1 Polyclonal Antibody 100 µg  905-731-100 $295.00
Background
The transcriptional repressor BMI-1 was first identified as a proto-oncogene that cooperates with c-myc in the generation of lymphomas in murine models. BMI-1 belongs to the Polycomb-group (PcG) family of proteins involved in axial patterning, hematopoeisis, cell growth, and senescence. A major target of BMI-1 is the INK4A/ARF locus which encodes tumor suppressor proteins p16 and p19ARF. Recent studies have also shown that BMI-1 is overexpressed in numerous human cancers, including lymphomas, breast, colorectal, and prostate cancers.

Table of Abbreviations

Abbreviated Name
BMI-1 pAb

Conjugate

Applications
ICC, WB

Isotype
not applicable

Product Image(s): click to enlarge

Purification
Peptide Affinity

Species Reactivity
H, M, R

Immunogen
Synthetic peptide derived from the sequence of human BMI-1

Host
Rabbit

Clone Number
not applicable

Positive Control
K562 Cell Lysates

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#

Citations
Launch Citation Database

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