Dkk-1 (human) EIA Kit

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Description Size Catalog# Price Quantity  
Dkk-1 (human) EIA Kit  1x96 well 900-151 $525.00  
Background
Dkk-1 (Dickkopf-1) is a secreted inhibitor of the canonical Wnt signaling pathway, which mediates a variety of cellular processes including the growth and development of osteoblasts. Dkk-1 disrupts the canonical pathway by binding to the LRP5/6 co-receptors, preventing interaction with Wnt, and facilitating the degradation of beta-catenin. Dkk-1 is overexpressed in multiple myeloma, increasing bone resorption and the appearance of osteolytic lesions characteristic of multiple myeloma.

Table of Abbreviations

Features

  • Ready-to-use liquid color-coded reagents
  • Fully quantitative results surpass semi-quantitative Western blot analysis
  • Reliable and reproducible results in just 3 hours
  • Validated with pathological and non-pathological samples

Product Image(s): click to enlarge
Dkk-1 EIA Kit

Applications
EIA

Range
7.81 - 500 pg/mL

Sample Size
100 µL

Cross Reactivites
human Dkk-1: 100%
<0.02%: Dkk-4 / GSK-3beta / beta-catenin / PIN 1

Sample Types
serum, plasma, and culture supernates

Samples Per Kit
39 in duplicate

Sensitivity
0.98 pg/mL

Species Reactivity
H

Time To Answer
3 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
Assay Layout
Kit Insert
MSDS

Product Manual

Product Name Catalog # Manual
Dkk-1 (human) EIA Kit 900-151  

Ordering Info
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Order by fax: 734-669-0134