Bax Monoclonal Antibody (4F11)

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Description Size Catalog# Price Quantity  
Bax Monoclonal Antibody (4F11) 100 µg  AAM-140E $295.00
Background
Bax is an appromimately 22 kDa pro-apoptotic protein belonging to the Bcl-2 family of proteins, which are characterized by the presence of at least one Bcl-2 homology (BH) domains. Bax normally resides in the cytoplasm, but following an apoptotic stimuli, Bax undergoes a conformational change and translocates to mitochondrial membranes where it inserts and mediates the release of cytochrome c. This activates caspase-3 and perpetuates the apoptotic cascade.

Table of Abbreviations

Abbreviated Name
Bax mAb (4F11)

Conjugate

Applications
IHC, IP, WB

Isotype
IgG2b

Purification
Protein A Affinity

Immunogen
Recombinant human Bax protein

Host
Mouse

Clone Number
4F11

Species Reactivity
H

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

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