13(S)-HODE EIA Kit

Brand: Assay Designs Print Page
Description Size Catalog# Price Quantity  
13(S)-HODE EIA Kit  1x96 well 900-108 $360.00  
13(S)-HODE EIA Kit  5x96 well 901-108 $1,440.00  
Background
The major human dietary poly-unsaturated fatty acid is linoleic acid, an essential fatty acid that can be metabolized to either 13-hydroxyoctadecadienoic acid [13(S)-HODE] via lipoxygenase or [13(R)-HODE] by p450 enzymes. Alternatively, cyclooxygenase metabolism of linoleic acid results in the production of hydroxyeicosatetraenoic acid [15(S)-HETE]. Changes in the intra-cellular ratio of 13(S)-HODE to 15(S)-HETE have been linked to a number of physiological conditions including cancer and cardiovascular disease. 13(S)-HODE helps to mediate cell adhesion and excessive proliferation that is critical in the formation of tumors and metastases, as well as the formation of atherogenic plaques.

Table of Abbreviations

Applications
EIA

Features

  • Validated in numerous matrices
  • Highly cited in peer-reviewed literature

Range
3.9 - 1,000 ng/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
13(S)-HODE: 100%
13(R)-HODE: 2.00%
13-KODE: 0.48%
Linoleic Acid: 0.31%
gamma-Linolenic Acid: 0.28%
9(S)-HODE: 0.13%
12(R)-HETE: 0.07%
15(S)-HETE: 0.03%
<0.01%: 12(S)-HETE / Arachidonic Acid / DGLA / 5(S)-HETE / PGE1

Sample Types
tissue culture media, serum, saliva, urine

Samples Per Kit
39 in duplicate per 96 well kit

Sensitivity
1.6 ng/mL

Species Reactivity
Species Independent

Time To Answer
4 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
AssayLayout

Product Manual

Product Name Catalog # Manual
13(S)-HODE EIA Kit 900-108   Kit Insert    MSDS   
13(S)-HODE EIA Kit 901-108   Kit Insert    MSDS   

Ordering Info
Click here to learn more about online ordering
Order by phone: 734-668-6113 or 877-423-4548
Order by e-mail: orders@assaydesigns.com
Order by fax: 734-669-0134