C1s (human, pro- and activated enzyme)

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Description Size Catalog# Price Quantity  
C1s (human, pro- and activated enzyme)  50 µg ABS 002-49-S $145.00  
C1s (human, pro- and activated enzyme)  200 µg ABS 002-49-02 $435.00  
C1s (human, pro- and activated enzyme)  1 mg ABS 002-49-1 $1,970.00  
Background
C1s proenzyme is a 79.8 kDa glycoprotein produced primarily by hepatocytes but also by other cells. The proenzyme is produced as a single-chain polypeptide of 688 amino acids. Upon activation the peptide is cleaved between R437 and I438 giving the activated enzyme consisting of two disulfide-linked chains, A chain (52.2 kDa) and B chain (27.7 kDa). The Ca-dependent catalytic subunit of the C1 complex (C1q, C1r, C1s) comprises of two C1s and two C1r molecules and this serine protease tetramer is responsible for the initial steps in the classical complement pathway, cleavage of C4 and C2.

Table of Abbreviations

Species Reactivity
H

Applications
EIA

Format
protein A/G purified (from culture supernatant)

Conjugate
Unconjugated BSA free

HostSpecies
Mouse

Isotype
IgG1/k

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

Product Manual

Product Name Catalog # Manual
C1s (human, pro- and activated enzyme) ABS 002-49-S  
C1s (human, pro- and activated enzyme) ABS 002-49-02  
C1s (human, pro- and activated enzyme) ABS 002-49-1  

Related Products

Product Name Catalog#
C1s (human, pro- and activated enzyme)
 		ABS 002-09

Citations
Launch Citation Database

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