15-deoxy-delta-12,14 PGJ2 Polyclonal Antibody

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Description Size Catalog# Price Quantity  
15-deoxy-delta-12,14 PGJ2 Polyclonal Antibody 100 µL  915-044 $345.00
Background
15-deoxy-Delta12,14-Prostaglandin J2 (15-d-PGJ2) is one of the ultimate dehydration products of PGD2, formed via the intermediate Delta12-PGJ2. 15-d-PGJ2 is physiologically present in body fluids at concentration of 10-12 to 10-9 M, but increases dramatically under stress such as infection and inflammation. 15-d-PGJ2 exerts both pro- and anti-inflammatory effects in a cell-type and concentration-dependent manner, with many of these effects mediated via binding to the gamma isoform of the peroxisome proliferators-activated receptor (PPAR-gamma). 15-d-PGJ2 appears to induce HO-1 expression by a PPAR-gamma-independent mechanism mediated by the generation of reactive oxygen species (ROS).

Table of Abbreviations

Applications
EIA

Conjugate

Isotype
not applicable

Purification
Sodium sulfate precipitation

Immunogen
15-deoxy-D12,14-Prostaglandin J2

Host
Rabbit

Clone Number
not applicable

Species Reactivity
Species Independent

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#
15-deoxy-delta-12,14 PGJ2 Polyclonal Antibody
 		915-043

Citations
Launch Citation Database

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