11-dehydro-TXB2 Polyclonal Antibody

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Description Size Catalog# Price Quantity  
11-dehydro-TXB2 Polyclonal Antibody lyoph  905-035 $65.00
Background
Thromboxane A2 (TXA2 ) is involved in platelet aggregation, vasoconstriction and reproductive functions, but has a half life of only 37 seconds under physiological conditions. Thromboxane B2 (TXB2) is the stable product of the non-enzymatic hydration of TXA2, thus the production of TXA2 in vivo is typically monitored by measurement of TXB2 and its metabolite 2,3-dinor TXB2. 11-dehydro-TXB2 is a major metabolite of Thromboxane B2 (TXB2) found in urine and plasma produced by its dehydrogenation by the enzyme 11-OH-dehydrogenase.

Table of Abbreviations

Species Reactivity
Species Independent

Applications
EIA

Format
antisera

Cross Reactivities
11-dehydro-TXB2 100%
PGD2 0.24%
TXB2 0.06%
<0.01% PGE2, 6-keto-PGF1a, PGF2a, 9a,11b-PGF2a, Arachidonic acid

HostSpecies
rabbit

Immunogen
11-dehydro-TXB2 conjugated to bovine albumin

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

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