8-iso-PGF2 alpha Polyclonal Antibody

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Description Size Catalog# Price Quantity  
8-iso-PGF2 alpha Polyclonal Antibody 100 µL  905-016 $255.00
Background
Prostaglandin F2alpha (PGF2alpha) is formed in a variety of cells from PGH2, which itself is synthesized from arachidonic acid by the enzyme prostaglandin synthetase. PGF2alpha is often viewed as an antagonist to PGE2 due to their opposing effects on various tissues. PGF2alpha is a potent bronchoconstrictor and has been implicated in asthma attacks. PGF2alpha is also involved in reproductive functions including corpus luteum regulation, uterine contractions, and sperm motility. This has led to its use in terminating pregnancies and inducing labor at term. High levels of PGF2alpha have also been associated with preeclampsia.

Table of Abbreviations

Abbreviated Name
8-iso-PGF2 alpha pAb

Conjugate

Applications
EIA

Isotype
not applicable

Purification

Immunogen
8-iso-Prostaglandin F2alpha conjugated to porcine thyroglobulin

Host
Rabbit

Clone Number
not applicable

Cross Reactivities
8-iso-PGF2a 100%
PGF1a 84.0%
PGF2a 5.0)%
PGE1 0.10%
6-keto-PGF1a 0.10%
TXB2 0.03%
13,14-dihydro-15-keto-PGF2a <0.01%
PGE3 <0.01%
PGB1 <0.01%
PGA2 <0.01%
6,15-diketo-13,14-dihydro-PGF1a <0.01%

Species Reactivity
Species Independent

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#
8-iso-PGF2 alpha Polyclonal Antibody
 		905-015

Citations
Launch Citation Database

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