15-deoxy-delta-12,14 PGJ2 Polyclonal Antibody

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Description Size Catalog# Price Quantity  
15-deoxy-delta-12,14 PGJ2 Polyclonal Antibody 100 µL  915-044 $345.00
Background
15-deoxy-delta12,14-Prostaglandin J2 is one of the ultimate dehydration products of PGD2. PGD2 is formed from PGH2 which itself is synthesized from arachidonic acid by the enzyme prostaglandin synthase. In the aqueous solution PGD2 forms PGJ2. Albumin or other serum proteins present in the sample will convert PGD2 to the isomeric compound, delta12-PGJ2. In males about 152 ng of delta12-PGJ2 is excreted in urine per day, and in women about half this amount is excreted. Excellent recent reviews of the biological actions of these compounds have been published. 15-d-PGJ2 has been shown as an inducer of adipogenesis and an activator of the gamma isoform of the peroxisome proliferation activated receptor (PPARgamma).

Applications
EIA

Format
1.0 mg/mL Rabbit IgG in PBS with 0.1% NaN3.

HostSpecies
rabbit

Immunogen
15-deoxy-D12,14-Prostaglandin J2

Isotype
Rabbit IgG

PurificationMethod
Sodium sulfate precipitation

Species Reactivity
Species Independent

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

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