2,3 dinor-6-keto-PGF1 alpha Affinity Resin

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Description Size Catalog# Price Quantity  
2,3 dinor-6-keto-PGF1 alpha Affinity Resin** (per ml pricing)   1-9 mls RES-110 $305.00  
Background
Prostacyclin (PGI2) is involved in platelet aggregation, vasoconstriction, and reproductive functions. PGI2 has a half life of 60 minutes in plasma but only 2 to 3 minutes in buffer. The production of PGI2 is typically monitored by measurement of 6-keto-PGF1 alpha and 2,3-dinor-6-keto-PGF1 alpha. 6-keto-PGF1 alpha is produced by thenon-enzymatic hydration of PGI2, and is further metabolized in urine to the 2,3-dinor derivative. A number of pharmaceuticals alter and/or inhibit the synthesis of PGI2. Methods to measure PGI2 in urine typically involve HPLC, gas chromatography/mass spectrometry or radioimmunoassay and enzyme immunoassay for 6-keto-PGF1 alpha.

Table of Abbreviations

Applications
Affinity Enrichment/Depletion

Species Reactivity
6-keto-PGF1a

ProductComments
**ADDITIONAL SIZES AVAILABLE, Call to inquire

Source
Sheep IgG Coupled to SepharoseŽ 4B

Purification
Protein G Affinity

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Product Manual

Product Name Catalog # Manual
2,3 dinor-6-keto-PGF1 alpha Affinity Resin** (per ml pricing) RES-110  

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