Chk1 Monoclonal Antibody (2G1D5)

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Description Size Catalog# Price Quantity  
Chk1 Monoclonal Antibody (2G1D5) 100 µg   905-770-100 $235.00
Background
The DNA damage checkpoint is a signal transduction pathway that has the ability to delay entry into mitosis. When DNA is damaged, the Check point kinases (CHKs) are known to act downstream of ATM to elicit appropriate responses such as cell cycle arrest. Chk1, for instance, is activated by ATM phosphorylation of serines 123, 178, 278, and 292 of the S phase-promoting cdc25A phosphatase and accelerates IR (ionizing radiation)?induced degradation of cdc25A.

Table of Abbreviations

Applications
WB

Species Reactivity
H, M, R

Conjugate

Isotype
IgG1

Product Image(s): click to enlarge

Purification
Protein G Affinity

Immunogen
Recombinant human Chk1 protein

Host
Mouse

Clone Number
2G1D2

Positive Control
LYC-HL100 HeLa Cell Lysate

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Product Name Catalog#
Chk1 Monoclonal Antibody (DCS-310)
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KAM-TF200

Citations
Launch Citation Database

Ordering Info
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