Beclin-1 Polyclonal Antibody

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Description Size Catalog# Price Quantity  
Beclin-1 Polyclonal Antibody 100 µg   905-721-100 $285.00
Background
Beclin-1 is a coiled-coil Bcl-2-interacting protein that functions in autophagy, the process of bulk degradation of cellular proteins. Beclin-1 is homologous to the yeast autophagy gene apg6, and is expressed at reduced levels in human breast carcinoma, suggesting that defects in autophagy proteins may contribute to the development or progression of tumors. Bcl-2 can inhibit Beclin-1-dependent autophagy in yeast and mammalian cells, suggesting that Bcl-2 functions as both an anti-autophagic and anti-apoptotic protein.

Table of Abbreviations

Applications
IHC, WB

Species Reactivity
H, M, R

Conjugate

Isotype
not applicable

Product Image(s): click to enlarge

Purification
Peptide Affinity

Immunogen
Synthetic peptide corresponding to sequence near the amino-terminus of human Beclin-1

Host
Rabbit

Clone Number
not applicable

Positive Control
rat brain

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

Ordering Info
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