NSE Polyclonal Antibody

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Description Size Catalog# Price Quantity  
NSE Polyclonal Antibody 200 ug   905-494 $265.00
Background
Enolase (NSE) is a glycolytic enzyme catalyzing the reaction pathway between 2- phosphoglycerate and phosphoenolpyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits. The alpha-subunit is expressed in most tissues and the beta-subunit only in muscle. The gamma-subunit is expressed primarily in neurons, normal, and neoplastic neuroendocrine cells.

Table of Abbreviations

Applications
IHC

Species Reactivity
H

Conjugate

Isotype
not applicable

Product Image(s): click to enlarge

Purification
Affinity Purified

Immunogen
Synthetic peptide derived from sequence near the carboxy-terminus of human NSE

Host
Rabbit

Clone Number
not applicable

Positive Control
human pancreas

Significance & Uses
Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2-phospho-glycerate and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits. The alpha-subunit is expressed in most tissues and the beta-subunit only in muscle. The gamma-subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms.

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Ordering Info
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