AIB1 Monoclonal Antibody (50B6)

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Description Size Catalog# Price Quantity  
AIB1 Monoclonal Antibody (50B6) 100 µg   905-706-100 $265.00
Background
AIB1 is a member of the p160/steroid receptor coactivator (SRC) family, named for its common amplification in breast cancer. Members of this family include a defined nuclear receptor box motif (LxxLL) that is critical for binding to nuclear hormone receptors, and two C-terminal activation domains that bind secondary coactivators such as the p300/CREB binding protein (CBP) and CARM-1 to confer acetyltransferase or methyltransferase downstream signals, respectively. AIB1 binds to estrogen receptor (ER), and its overexpression in hormone-responsive cancers and frequent amplification in breast and other cancers make it a focus for the treatment of cancer and the study of hormone receptor signaling.

Table of Abbreviations

Applications
WB

Species Reactivity
H

Conjugate

Isotype
not available

Product Image(s): click to enlarge

Purification
Protein G Affinity

Immunogen
Recombinant human AIB1 protein

Host
Mouse

Clone Number
50B6

Positive Control
MCF-7 cell lysates

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

Ordering Info
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