IGF-1 Receptor (phospho-Tyr1316) Monoclonal Antibody (2B9)

Brand: Assay Designs Print Page
Description Size Catalog# Price Quantity  
IGF-1 Receptor (phospho-Tyr1316) Monoclonal Antibody (2B9) 100 µg   905-643 $375.00
Background
Insulin-like growth factor-I (IGF-I) is a polypeptide hormone similar in structure to insulin. It is involved in regulation of neuronal growth and development in the central and peripheral nervous system. IGF-1 is a potent inhibitor of apoptosis in neurons, and activates the Akt signaling pathway via the IGF-1R and Insulin receptors. The IGF-1R acts as a receptor for IGF-1 and the related IGF-2, and is subject to autophosphorylation on multiple tyrosine residues that regulate receptor activation and assembly of signal transduction complexes.

Table of Abbreviations

Applications
EIA, WB

Species Reactivity
H

Conjugate

Isotype
IgG1

Product Image(s): click to enlarge

Purification
Thiophilic adsorption and size exclusion chromatography

Immunogen
Synthetic phospho-peptide derived from the sequence of human IGF-1 Receptor, conjugated to hemocyanin

Host
Mouse

Clone Number
2B9

Positive Control
Insulin-treaed HEK 293 cells

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#
IGF-1 Receptor Monoclonal Antibody (7G11)
905-644
IGF-I (human) EIA Kit
900-150
IGF-I Recombinant Human Protein
908-059

Citations
Launch Citation Database

Ordering Info
Click here to learn more about online ordering
 Order by phone: 734-668-6113 or 877-423-4548
Order by e-mail: orders@assaydesigns.com
Order by fax: 734-669-0134