PIP (Phosphatidylinositol-4 monophosphate) Monoclonal Antibody

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Description Size Catalog# Price Quantity  
PIP (Phosphatidylinositol-4 monophosphate) Monoclonal Antibody 0.5 mL   915-045 $260.00
Background
Metabolism of inositol phospholipids by intracellular signaling mediators is fundamental to signal transduction in eukaryotic cells. PI-4,5-P2 (PIP2) can be synthesized by phosphorylation of PI-4-P by type I phosphatidylinositol phosphate kinase (PIP5K I), or phosphorylation of PI-5-P by type II PIPK (PIP4K II). PI-4,5-P2 regulation of cellular calcium levels involves its hydrolysis by Phospholipase C (PLC) to produce inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG), which serve as second messengers in the import of calcium via IP3-sensitive ion channels and in the activation of PKC, respectively.

Table of Abbreviations

Applications
EIA

Species Reactivity
Species Independent

Conjugate

Isotype
IgM

Purification

Immunogen
PIP from bovine spinal cord

Host
Mouse

Clone Number
not available

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Ordering Info
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