CCR8 (EL) Polyclonal Antibody

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Description Size Catalog# Price Quantity  
CCR8 (EL) Polyclonal Antibody 100 µg   905-278 $240.00
Background
Human immunodeficiency virus (HIV) requires co-receptors, in addition to CD4, to infect target cells. Some G protein coupled receptors such as CCR5, CCR4, CCR3, CCR2b, and CCR8 have been identified as HIV co-receptors. Among them, CCR5 (CCCKR-5) is a principal co-receptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells. CCR5 is required for the infection by HIV-1, HIV-2, and SIV. The amino-terminal domain and the extracellular loops of CCR5 serve as HIV binding sites.

Table of Abbreviations

Applications
WB

Species Reactivity
H

Conjugate

Isotype
not applicable

Purification
Peptide Affinity

Immunogen
Synthetic peptide derived from the sequence of the second extracellular loop (EL) of human CCR8

Host
Rabbit

Clone Number
not applicable

Product Image(s): click to enlarge

PositiveControls
Human spleen tissue lysates

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

Ordering Info
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