CCR5 (NT) Polyclonal Antibody

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Description Size Catalog# Price Quantity  
CCR5 (NT) Polyclonal Antibody 100 µg   905-277 $275.00
Background
Human immunodeficiency virus (HIV) requires co-receptors, in addition to CD4, to infect target cells. Some G protein coupled receptors such as CCR5, CCR4, CCR3, CCR2b, and CCR8 have been identified as HIV co-receptors. Among them, CCR5 (CCCKR-5) is a principal co-receptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells. CCR5 is required for the infection by HIV-1, HIV-2, and SIV. The amino-terminal domain and the extracellular loops of CCR5 serve as HIV binding sites.

Table of Abbreviations

Applications
IHC, WB

Species Reactivity
H

Conjugate

Isotype
not applicable

Purification
DEAE

Immunogen
Synthetic peptide derived from sequence near the amino-terminus of human CCR5

Host
Rabbit

Clone Number
not applicable

Product Image(s): click to enlarge

PositiveControls
THP-1 whole cell lysates

For research use only, not for diagnostic or therapeutic use.

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