Dkk-1 (mouse) EIA Kit

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Description Size Catalog# Price Quantity  
Dkk-1 (mouse) EIA Kit   1x96 Well 900-172 $445.00  
Background
Dkk-1 (Dickkopf-1) is a secreted inhibitor of the canonical Wnt signaling pathway, which mediates a variety of cellular processes including the growth and development of osteoblasts. Dkk-1 disrupts the canonical pathway by binding to the LRP5/6 co-receptors, preventing interaction with Wnt, and facilitating the degradation of beta-catenin. Dkk-1 is overexpressed in multiple myeloma, increasing bone resorption and the appearance of osteolytic lesions characteristic of multiple myeloma.

Table of Abbreviations

Applications
EIA

Species Reactivity
M

Features

  • Sensitive - measure as little as 116.7 pg/mL Dkk-1
  • Higher Throughput - assay up to 40 samples in duplicate in just 3 hours
  • Accurate - fully quantitative results and no reactivity to related proteins

Range
125 - 4000 pg/mL

Product Image(s): click to enlarge

Cross Reactivities
mouse Dkk-1 100%... human Dkk-1 0.47%, <0.03% mouse Dkk-2, Dkk-4, Kremen-1, Kremen-2, LRP-6, Sgy-1, and human Beta-Catenin, GSK

Sample Types
CS, P, S

Samples Per Kit
40 in duplicate

Sensitivity
116.7 pg/mL

Time To Answer
3 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
Assay Layout
Kit Insert
MSDS

Product Manual

Product Name Catalog # Manual
Dkk-1 (mouse) EIA Kit 900-172  

Ordering Info
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