Akt (pSer473) Singleplex MultiBead Kit

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Akt (pSer473) Singleplex MultiBead Kit 1x96 well   985-010 $175.00
Background

Buy any MultiBead Singleplex kit and receive a free companion MultiBead buffer pack (987-001 or 987-002).


Please reference promo code "MBPACK" when placing order. Offer expires 11/30/09. Cannot be combined with other discount offers. Void where prohibited by law or institutional policy. Limit two buffer packs per order.

Akt activation is triggered by phosphorylation at two key residues: Thr308 by PDK1, and Ser473 by PDK2, now identified as mTOR. Deregulation of Akt signaling has been associated with cancer, diabetes, and schizophrenia. Akt1 is the cellular homologue of the murine thymoma retroviral oncogene v-akt, and its role in anti-apoptotic and pro-mitotic pathways has made Akt a molecular target for anti-cancer therapeutic intervention Mitotic substrates of Akt include GSK-3beta, p21CIP1, and p27KIP1, cell cycle inhibitors negatively regulated by Akt phosphorylation.

Learn more about our MultiBead kits >>

Table of Abbreviations

Applications
Multiplex

Species Reactivity
H

Features

  • Multiplexing capability - save time and conserve precious samples
  • Quantitative data - obtain accurate results with included standards
  • Proprietary conjugation chemistry - detect low abundant, large, and small molecule analytes with improved sensitivity
  • Compatibility with common equipment - conveniently run samples on dual-laser flow cytometers

Range
2.74 - 2000 U/mL

Sensitivity
2.0 U/mL

Sample Types
CL

Samples Per Kit
39 in duplicate

Time To Answer
<4.5 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
Assay Layout
Kit Insert
MSDS
Software Instruction Manual (2.63 MB)

Related Products

Product Name Catalog#
Akt Singleplex MultiBead Kit
985-009
Akt3 Monoclonal Antibody (9B2)
905-821
HSP / Chaperone 8-Plex MultiBead Kit
980-002
HSP/Chaperone MultiBead Buffer Pack
987-002
Hsp27 (pSer15) Singleplex MultiBead Kit
985-011
Hsp27 (pSer82) Singleplex MultiBead Kit
985-012
Hsp40 Singleplex MultiBead Kit
985-014
Hsp60 Singleplex MultiBead Kit
985-015
Hsp70 Singleplex MultiBead Kit
985-016
Hsp90 alpha Singleplex MultiBead Kit
985-017

Citations
Launch Citation Database

Ordering Info
Click here to learn more about online ordering
 Order by phone: 734-668-6113 or 877-423-4548
Order by e-mail: orders@assaydesigns.com
Order by fax: 734-669-0134