APC-PCI (human) ELISA

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Description Size Catalog# Price Quantity  
APC-PCI (human) ELISA 1 x 96 well   KIT 040 $1,195.00
Background
Activated protein C - protein C inhibitor (APC-PCI) complex is formed in the blood upon activation of protein C (PC) and is thus a marker of PC activation. As soon as APC is produced within circulation, it undergoes inactivation by reacting with serpins (protein C, alpha1-antitrypsin, alpha2-antiplasmin, and C1-esterase inhibitor) which are also present in the blood. Of these, PCI appears to be of the greatest physiological importance. APC-PCI is studied in relation to sepsis and thrombosis. The median concentration of APC-PCI complex measured in plasma from healthy volunteers was 0.13 ng/mL (range 0.07-0.26 ng/mL), blood samples being collected into acid citrate to prevent further complex formation after sampling.

Table of Abbreviations

Applications
EIA

Species Reactivity
H

Time to Answer
4 hours

Sample Types
P

Sensitivity
0.0017 ng/mL

Range
0.016 - 1 ng/mL

Features (bullet points)

  • Innovative - first & only commercially available APC-PCI ELISA Kit
  • Flexible - pre-coated microtiter plates provide easy experimental design
  • Convenient - product stored at 4C

Samples per Kit
40 in duplicate

For research use only, not for diagnostic or therapeutic use.

Documentation
APC-PCI Flyer

Related Products

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alpha1-Antitrypsin (alpha1-AT) (human) Monoclonal Antibody (4E5)
HYB 185-02
alpha1-Antitrypsin (alpha1-AT) (human, native, denatured) Monoclonal Antibody (3B7)
HYB 191-01

Citations
Launch Citation Database

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