Chk2 (NT) Polyclonal Antibody

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Description Size Catalog# Price Quantity  
Chk2 (NT) Polyclonal Antibody 100 µg   905-296 $235.00
Background
The DNA damage checkpoint is a signal transduction pathway that has the ability to delay entry into mitosis. When DNA is damaged, the Check point kinases (CHKs) are known to act downstream of ATM to elicit appropriate responses such as cell cycle arrest. Chk1, for instance, is activated by ATM phosphorylation of serines 123, 178, 278, and 292 of the S phase-promoting cdc25A phosphatase and accelerates IR (ionizing radiation)?induced degradation of cdc25A.

Table of Abbreviations

Applications
ICC, WB

Species Reactivity
H, M, R

Conjugate

Isotype
not applicable

Purification
Immunoaffinity

Immunogen
Synthetic peptide derived from sequence near the amino-terminus of human Chk2

Host
Rabbit

Clone Number
not applicable

Product Image(s): click to enlarge

PositiveControls
Jurkat or K562 cell lysates

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#
Chk2 Monoclonal Antibody (DCS-270)
KAM-CC112E
Chk2 Monoclonal Antibody (DCS-273)
KAM-CC113E
Chk2 Recombinant Human Protein
PPK-419
DNA Damage ELISA Kit
EKS-350
p53 R2 (NT) Polyclonal Antibody
905-301

Citations
Launch Citation Database

Ordering Info
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