LTB4 Polyclonal Antibody

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Description Size Catalog# Price Quantity  
LTB4 Polyclonal Antibody lyoph   905-037 $90.00
Background
Leukotrienes are major products of 5-lipoxygenase metabolism of arachidonic acid. Leukotriene B4 (LTB4) stimulates leukocyte functions including lysosomal enzyme release, adhesion, and aggregation of polymorphonuclear leukocytes. LTB4 has been implicated as a potent mediator of inflammatory diseases and immunoregulation. The cysteinyl leukotrienes (LTC4, LTD4, and LTE4) are formed by addition of cysteine derivatives to LTA4. The conversion of LTA4 to LTC4 by the enzyme LTC4 synthase limits the rate of cysteinyl leukotriene formation. Cysteinyl leukotrienes are potent lipid mediators in inflammation, inducing smooth muscle contractions and increased capillary permeability.

Table of Abbreviations

Applications
EIA

Species Reactivity
Species Independent

Conjugate

Isotype
not applicable

Purification

Immunogen
(see spec sheet)

Host
Rabbit

Clone Number
not applicable

Cross Reactivities
LTB4 100%
<1.00%: LTC4, LTD4, LTE4, 5-HETE, 12-HETE, 15-HETE, PGA1, PGA2, PGB1, PGB2, PGD2, PGE1, PGE2, 6-keto-PGF1a, 6-keto-PGE1, 13,14-dihydro-15-keto-PGF2a, 13,14-dihydro-15-keto-PGE2, TXB2, Bicyclo-PGE2

For research use only, not for diagnostic or therapeutic use.

Documentation
MSDS
Spec Sheet

Related Products

Product Name Catalog#

Citations
Launch Citation Database

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