FLIPgamma/delta (CT) Polyclonal Antibody

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Description Size Catalog# Price Quantity  
FLIPgamma/delta (CT) Polyclonal Antibody 100 µg   905-226 $285.00
Background
The cellular FLICE-like inhibitory protein, cFLIP, is a cellular homologue of the viral protein, vFLIP. cFLIP contains two death effector domains (DEDs) and is expressed as either a short or long splice variant called cFLIPs and cFLIPL, respectively. cFLIP acts as a caspase-8 dominant negative regulator, blocking apoptosis induced by the oligimerization of the adapter protein, FADD. cFLIP interacts with FADD and caspase-8 through their respective DEDs.

Table of Abbreviations

Applications
IHC, WB

Species Reactivity
H, MO

Conjugate

Isotype
not applicable

Purification
Immunoaffinity

Immunogen
Synthetic peptide derived from sequence near the carboxy-terminus of human FLIP delta/FLIP short form

Host
Rabbit

Clone Number
not applicable

Product Image(s): click to enlarge

PositiveControls
Jurkat cell lysates

For research use only, not for diagnostic or therapeutic use.

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