Caspase-3 Colorimetric Detection Kit

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Description Size Catalog# Price Quantity  
Caspase-3 Colorimetric Detection Kit 1x96 well   907-013 $360.00
Background
The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or ?executioner? caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

Table of Abbreviations

Applications
Detection

Species Reactivity
Species Independent

Features

  • Results in 3 hours

Range
76 - 933 Units/mL

Sample Size
50 µL

Product Image(s): click to enlarge

Samples Per Kit
37 in duplicate per 96 well kit

Sensitivity
16.4 Units/mL

For research use only, not for diagnostic or therapeutic use.

Documentation
Assay Layout
Kit Insert
MSDS

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Citations
Launch Citation Database

Ordering Info
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