TNF-alpha (human) EIA Kit

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Description Size Catalog# Price Quantity  
TNF-alpha (human) EIA Kit   1x96well 900-099 $425.00  
TNF-alpha (human) EIA Kit   5x96well 901-099 $1,660.00  
TNF-alpha (human) EIA Kit   10x96well 902-099 $2,905.00  
Background
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Tumor necrosis factor alpha (TNFalpha), also known as cachectin, is a 17.5 kDa 157 amino acid member of the TNF superfamily of cytokines that is a potent lymphoid factor with effects on a wide range of target cells. Active TNFalpha is produced in both soluble and membrane-anchored trimers by macrophages, NK cells, and T- and B-lymphocytes. TNF exerts proinflammatory signals via binding and inducing trimerization of TNF-receptor1 (TNF-R1) expressed on most normal and transformed cells, or to TNF-receptor 2 (TNF-R2), expressed on endothelial and most immune cells. TNF signaling regulates hematopeiesis, differentation, endothelial cell activation, apoptosis, lipid metabolism, tumor progression, and immune suveillance, and dysregulation of TNF or its receptors is implicated in numerous disease states including cancer, osteoporosis, autoimmune disease, diabetes, and atherosclerosis.

Table of Abbreviations

Applications
EIA

Species Reactivity
H

Features

  • Stable color coded reagents
  • Sensitive to 8.4 pg/mL

Range
15.63 - 1,000 pg/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
human TNF-alpha 100%
Unaffected by: human TNF-beta / human sTNF RI / human sTNF RII / mouse TNF-alpha / mouse sTNF RI / mouse sTNF RII / rat TNF-alpha / porcine TNF-alpha

Sample Types
culture media, serum, EDTA plasma

Samples Per Kit
39 in duplicate per 96 well kit

Sensitivity
8.43 pg/mL

Time To Answer
4 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
AssayLayout
Kit Insert
MSDS

Product Manual

Product Name Catalog # Manual
TNF-alpha (human) EIA Kit 900-099  
TNF-alpha (human) EIA Kit 901-099   Kit Insert    
TNF-alpha (human) EIA Kit 902-099   Kit Insert    

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Citations
Launch Citation Database

Ordering Info
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