Cysteinyl Leukotriene EIA Kit

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Description Size Catalog# Price Quantity  
Cysteinyl Leukotriene EIA Kit   1x96 well 900-070 $345.00  
Cysteinyl Leukotriene EIA Kit   5x96 well 901-070 $1,395.00  
Background
Leukotrienes are major products of 5-lipoxygenase metabolism of arachidonic acid. Leukotriene B4 (LTB4) stimulates leukocyte functions including lysosomal enzyme release, adhesion, and aggregation of polymorphonuclear leukocytes. LTB4 has been implicated as a potent mediator of inflammatory diseases and immunoregulation. The cysteinyl leukotrienes (LTC4, LTD4, and LTE4) are formed by addition of cysteine derivatives to LTA4. The conversion of LTA4 to LTC4 by the enzyme LTC4 synthase limits the rate of cysteinyl leukotriene formation. Cysteinyl leukotrienes are potent lipid mediators in inflammation, inducing smooth muscle contractions and increased capillary permeability.

Normalize urine samples to creatinine with our Creatinine Colorimetric Detection Kit.

Table of Abbreviations

Applications
EIA

Species Reactivity
Species Independent

Features

  • Fast- results in just 4 hours
  • Easy - liquid color-coded reagents reduce error
  • Safe - non-radioactive measurement of LTC4/D4/E4
  • Reproducible - less than 5% inter- and intra-assay variation

Range
78.1 - 2,500 pg/mL

Sample Size
100 µL

Product Image(s): click to enlarge

Cross Reactivities
LTC4 100%
LTD4 115.12%
LTE4 62.7%
LTB4 1.16%
Arachidonic Acid 0.61%
PGE2 0.48%
6-trans-LTB4 0.45%
TXB2 0.28%
<0.20%: 20-OH-LTB4 / PGF2alpha / 6-keto-PGF1alpha / PGD2 / 5-HETE / 12-HETE / 15-HETE

Sample Types
culture media, urine

Samples Per Kit
38 in duplicate per 96 well kit

Sensitivity
26.6 pg/mL

Time To Answer
4 hours

For research use only, not for diagnostic or therapeutic use.

Documentation
AssayLayout

Product Manual

Product Name Catalog # Manual
Cysteinyl Leukotriene EIA Kit 900-070   Kit Insert     MSDS    
Cysteinyl Leukotriene EIA Kit 901-070   Kit Insert     MSDS    

Related Products

Product Name Catalog#
12(S)-HETE EIA Kit
900-050
12(S)-HETE EIA Kit
901-050
13(S)-HODE EIA Kit
900-108
15(S)-HETE EIA Kit
900-051
15(S)-HETE EIA Kit
901-051
Creatinine Colorimetric Detection Kit
907-030
LTB4 EIA Kit
900-068
PGE2 EIA Kit
900-001

Citations
Launch Citation Database

Ordering Info
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