N-Cadherin Polyclonal Antibody

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Description Size Catalog# Price Quantity  
N-Cadherin Polyclonal Antibody 100 µg  915-004 $295.00
Background
The Ca2+-dependent intercellular adhesion Cadherin molecules play an important role in cell-cell interaction, histogenesis and cellular transformation, with their function regulated through an association with the actin cytoskeleton by a complex of cytoplasmic proteins called the catenins (alpha, beta, gamma). Endogenous kinases and phosphatases indirectly regulate N-cadherin function, and tyrosine phosphorylation of beta-catenin complexed with N-cadherin results in dissociation of N-cadherin from actin, making N-cadherin an integral adhesion molecule regulated by protein-protein interactions and phosphorylation/dephosphorylation events.

Table of Abbreviations

Abbreviated Name
N-Cadherin pAb

Conjugate

Applications
IHC

Isotype
not applicable

Product Image(s): click to enlarge

Purification
Peptide Affinity

Immunogen
Synthetic peptide derived from a part of Human N-Cadherin

Host
Rabbit

Clone Number
not applicable

Source
Rabbit pAb

Species Reactivity
H

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#
Catenin-beta (total) EIA Kit
 		900-135
Catenin-beta Monoclonal Antibody (12F7)
 		KAM-ST001E

Citations
Launch Citation Database

Ordering Info
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