Hsp70 (Hsp72) Monoclonal Antibody (C92F3A-5), FITC Conjugate

Brand: Stressgen

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Description	Size	Catalog#	Price	Quantity
Hsp70 (Hsp72) Monoclonal Antibody (C92F3A-5), FITC Conjugate	200 痢	SPA-810FIF	$350.00
Hsp70 (Hsp72) Monoclonal Antibody (C92F3A-5), FITC Conjugate	50 痢	SPA-810FID	$150.00

Background

The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

Table of Abbreviations

Conjugate
FITC

Isotype
IgG1

Purification
Protein G Affinity

Immunogen
Native human Hsp70 protein

Host
Mouse

Applications
Flow

Clone Number
C92F3A-5

Product Image(s): click to enlarge

Species Reactivity
H, M, R, BE, B, C, CH, D, F, GP, HA, MO, P, RB, S, A

For research use only, not for diagnostic or therapeutic use.

Documentation
MSDS

Product Manual

Product Name	Catalog #	Manual
Hsp70 (Hsp72) Monoclonal Antibody (C92F3A-5), FITC Conjugate	SPA-810FIF	Spec Sheet
Hsp70 (Hsp72) Monoclonal Antibody (C92F3A-5), FITC Conjugate	SPA-810FID	Spec Sheet

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Hsp70 (Hsp72) Monoclonal Antibody (C92F3A-5)	SPA-810
Hsp70 (Hsp72) Monoclonal Antibody (C92F3A-5), DyLight(TM) 488 Conjugate	SPA-810-488
Hsp70 (Hsp72) Monoclonal Antibody (C92F3A-5), R-Phycoerythrin Conjugate	SPA-810PE
Hsp70 High Sensitivity ELISA Kit	EKS-715

Citations
Launch Citation Database

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Hsp70 (Hsp72) Monoclonal Antibody (C92F3A-5), FITC Conjugate