Nitrotyrosine Monoclonal Antibody (7A5)

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Description Size Catalog# Price Quantity  
Nitrotyrosine Monoclonal Antibody (7A5) 100 µg   905-763-100 $275.00
Background
The enzymatic conversion of arginine to citrulline by nitric oxide synthase (NO Synthase) leads to the formation of nitric oxide (NO). Peroxynitrite is formed following reaction of NO with superoxide, producing a potent oxidant that reacts with a variety of biological molecules, including tyrosine residues in proteins. Tyrosine nitration can inactivate enzymes and receptors that depend on tyrosine residues for their activity. Nitration prevents phosphorylation of tyrosine residues important for signal transduction.

Table of Abbreviations

Applications
EIA, WB

Species Reactivity
H, M, R, C

Conjugate

Isotype
IgG1

Product Image(s): click to enlarge

Purification
Thiophilic adsorption and size exclusion chromatography

Immunogen
KLH modified with Nitrotyrosine

Host
Mouse

Clone Number
7A5

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#
Phosphotyrosine Monoclonal Antibody (6D12)
KAM-TK150F
Phosphotyrosine Polyclonal Antibody
KAP-TK155E

Citations
Launch Citation Database

Ordering Info
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