PIST Polyclonal Antibody

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Description Size Catalog# Price Quantity  
PIST Polyclonal Antibody 100 µg  905-724-100 $295.00
Background
Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway, is important for normal growth control and may be defective in tumor cells. Golgi-associated PIST (PDZ domain protein interacting specifically with TC10) has been characterized by its ability to bind and regulate the expression of membrane associated proteins. A neural isoform of PIST (nPIST) has been linked to autophagy and neurodegenerative disease by mediating the interaction between the delta2-glutamate receptor and Beclin-1, a Bcl-2-interacting protein homolog of the yeast autophagy gene apg6.

Table of Abbreviations

Conjugate

Applications
IHC, WB

Isotype
not applicable

Product Image(s): click to enlarge

Purification
Peptide Affinity

Species Reactivity
H, M, R

Immunogen
Synthetic peptide corresponding to sequence near the carboxy-terminus of human PIST

Host
Rabbit

Clone Number
not applicable

Positive Control
Rat colon

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Ordering Info
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