Crystallin, gamma Native Bovine Protein

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Crystallin, gamma Native Bovine Protein  200 µg SPP-240F $40.00  
Crystallin, gamma Native Bovine Protein  1000 µg SPP-240J $105.00  
Background
The crystallins are structural proteins most highly expressed in lens fiber cells of the vertebrate eye. The crystallins are divided into two subfamilies: the alpha-crystallins (alphaA and alphaB) which are members of the small heat shock protein superfamily, also functioning as molecular chaperones; and the evolutionarily-linked superfamily of beta- and gamma-crystallins which comprise the majority of soluble protein in the lens, and contribute to the transparency and refractive properties of lens structure. There are four major gamma-crystallin classes: terrestrial (gammaA-F); aquatic (fish-gammaM); gammaS; and gammaN, a betagamma-hybrid crystallin. The beta- and gamma-crystallins share structural homology in the presence of four ?modified Greek key? betagamma-motifs, but differ in that monomeric gamma-crystallins lack N-terminal extensions present in beta-crystallins that promote oligomerization. Alterations in gamma-crystallin gene expression leads to aggregation of misfolded protein in the lens, and has been linked to the development of congenital cataracts in humans. The predicted molecular weight of bovine gamma-crystallin is approximately 20-21 kDa.

Table of Abbreviations

Abbreviated Name
Crystallin, gamma Native Bovine Protein

Expression System
Bovine eye lens

Species Reactivity
not applicable

Applications
WB Control

Purification
Multi-step chromatography

Source
Bovine

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Product Manual

Product Name Catalog # Manual
Crystallin, gamma Native Bovine Protein SPP-240F  
Crystallin, gamma Native Bovine Protein SPP-240J  

Related Products

Product Name Catalog#
Crystallin, alpha A Native Bovine Protein
 		SPP-226
Crystallin, alpha B Native Bovine Protein
 		SPP-227
Crystallin, beta L Native Bovine Protein
 		SPP-236
Crystallin, beta Native Bovine Protein **SALE**
 		SPP-235

Citations
Launch Citation Database

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