Pax3 Monoclonal Antibody (C2)

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Description Size Catalog# Price Quantity  
Pax3 Monoclonal Antibody (C2) 100 µg  905-688-100 $295.00
Background
Pax3 is a member of the paired box family of nuclear transcription factors that function in the transcriptional control of pattern development during embryogenesis. Pax3 is characterized by a conserved N-terminal paired box DNA binding domain, and a C-terminal transcriptional activation domain. In humans, loss of function mutations in Pax3 are associated with type I and type III Waardenburg Syndrome, characterized by varying degrees of developmental abnormalities in facial structure, pigmentation, limb development, and hearing. Translocation t(2;13) of the Pax3 loci to the fork head (FKHR) transcription factor gene results in the creation of a Pax3-FKHR fusion gene with transcriptional hyperactivity manifested in alveolar rhabdomyosarcoma.

Table of Abbreviations

Abbreviated Name
Pax3 mAb (C2)

Conjugate

Applications
WB

Isotype
IgG2¦Á

Product Image(s): click to enlarge

Purification
Protein G Affinity

Immunogen
Synthetic peptide derived from a sequence near the carboxy-terminus of quail Pax-3

Host
Mouse

Clone Number
C2

Positive Control
human (624 mel nuclear extract)

Species Reactivity
H

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

Ordering Info
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