Smac/DIABLO Monoclonal Antibody (79-1-83)

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Description Size Catalog# Price Quantity  
Smac/DIABLO Monoclonal Antibody (79-1-83) 100 µg  905-684-100 $295.00
Background
Smac/DIABLO is one of the pro-apoptotic proteins normally found in the intermembrane space of the mitochondria. In response to apoptotic stimuli, Smac/DIABLO is released into the cytosol resulting in permeabilization of the mitochondrial membrane. Cytosolic Smac/DIABLO activates caspase-9 by binding IAP proteins. Changes in the expression level of Smac/DIABLO have been demonstrated in a number of human cancers including melanoma, ovary, and prostate.

Table of Abbreviations

Abbreviated Name
Smac/DIABLO mAb (79-1-83)

Conjugate

Applications
WB

Isotype
IgG2b

Product Image(s): click to enlarge

Purification
Protein G Affinity

Immunogen
Recombinant full length human Smac/DIABLO

Host
Mouse

Clone Number
79-1-83

Positive Control
Human (HeLa, Jurkat, and 293 cell lysates) and Monkey (Vero cell lysates)

Species Reactivity
H, MO

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

Ordering Info
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