Insulin Receptor beta Monoclonal Antibody (C18C4)

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Description Size Catalog# Price Quantity  
Insulin Receptor beta Monoclonal Antibody (C18C4) 100 µg  905-683-100 $295.00
Background
The Insulin Receptor (InsR) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. InsR is activated upon binding of the peptide hormone insulin, leading to autophosphorylation of tyrosine residues 1146, 1150, and 1151 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residues 960, 972, 1316, and 1322 regulate the assembly of signal transduction complexes.

Table of Abbreviations

Applications
WB

Product Image(s): click to enlarge

Format
PBS, pH 7.2, 0.09% azide, in 50% glycerol.

Host Species
mouse

Immunogen
Recombinant cytoplasmic domain of human Insulin Receptor beta

Positive Control
Human (MCF-7), rat (Rat-2), and mouse (L-929)

Purification Method
Protein G Affinity

Species Reactivity
H, M, R, B, HA, P, S, RB

Clone
C18C4

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

Ordering Info
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