Hsp70 Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Hsp70 Polyclonal Antibody  50 µg SPA-763D $210.00  
Hsp70 Polyclonal Antibody  200 µg SPA-763F $345.00  
Background
The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

Table of Abbreviations

Conjugate

Applications
WB

Isotype
not applicable

Purification

Immunogen
Recombinant salmon Hsp70 protein

Host
Rabbit

Clone Number
not applicable

PositiveControls
Hsp70 (Hsp72) Protein, Catalog Number SPP-763
HeLa Cell Lysate, Catalog Number LYC-HL100

Species Reactivity
H, M, R, B, C, CH, D, F

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Product Manual

Product Name Catalog # Manual
Hsp70 Polyclonal Antibody SPA-763D  
Hsp70 Polyclonal Antibody SPA-763F  

Related Products

Product Name Catalog#
HeLa Cell Lysate
 		LYC-HL100F
Hsp70 (Hsp72) Active Recombinant Protein
 		SPP-763
Hsp70 (Hsp72) Monoclonal Antibody (C92F3A-5)
 		SPA-810
Hsp70 (Hsp72) Monoclonal Antibody (C92F3A-5), DyLight(TM) 488 Conjugate
 		SPA-810-488
Hsp70 (Hsp72) Monoclonal Antibody (C92F3A-5), R-Phycoerythrin Conjugate
 		SPA-810PE

Citations
Launch Citation Database

Ordering Info
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