Jnk1 (SAPK) Monoclonal Antibody (5D10)

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Description Size Catalog# Price Quantity  
Jnk1 (SAPK) Monoclonal Antibody (5D10) 100 µg  905-649 $385.00
Background
The Stress-activated protein kinases alpha and gamma (SAPKalpha and gamma), also know as c-Jun NH2-terminal kinases 1 and 2 (Jnk1/2) are serine/ threonine protein kinase belonging to the MAP kinase family. The extracellular stimuli leading to cell stress include inflammatory cytokines (via Rho and Rac), growth factors, protein synthesis inhibitors and osmotic stress amongst others. Both Jnk1 and Jnk2 must be dually phosphorylated in the activation loop, at threonine 183 and tyrosine 185, to achieve full enzymatic activity.

Table of Abbreviations

Abbreviated Name
Jnk1 mAb (5D10)

Conjugate

Isotype
IgG1

Product Image(s): click to enlarge

Applications
EIA, IHC, WB

Purification
Thiophilic adsorption and size exclusion chromatography

Immunogen
Synthetic peptide derived from sequence near the amino terminus of Jnk1, conjugated to hemocyanin

Host
Mouse

Clone Number
5D10

Species Reactivity
H, M, C

Positive Control
Untreated HepG2 cells

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

Ordering Info
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