eNOS (phospho-Ser1177) Monoclonal Antibody (15E2)

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Description Size Catalog# Price Quantity  
eNOS (phospho-Ser1177) Monoclonal Antibody (15E2) 100 µg  905-657 $395.00
Background
Nitric oxide (NO) is synthesized from L-arginine, oxygen, and NADPH by three known isoforms of heme-containing flavoproteins termed NO synthases (NOS I-III). Analysis of cDNA clones has identified three distinct NOS genes in mammals: neuronal (nNOS/NOS-I), endothelial (eNOS/NOS-III), and inducible (iNOS/NOS-II). eNOS and nNOS are constitutively expressed, agonist-triggered, Ca2+/calmodulin-dependent, and are inhibited by L-arginine analogues (L-NNA, L-NMMA). They are expressed in endothelium, adrenal glands, brain, and platelets. iNOS is inducible, Ca2+/calmodulin-independent, and also inhibited by NMMA and L-NNA. It is expressed in macrophages, hepatocytes, tumor cells, vascular smooth muscle and endothelial cells.

Table of Abbreviations

Product Image(s): click to enlarge
western blot

Applications
EIA, WB

Clone Number
15E2

Species Reactivity
H, M

Immunogen
Synthetic phospho-peptide derived from the sequence of eNOS, conjugated to KLH

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#
eNOS Polyclonal Antibody
 		KAP-NO002
eNOS rabbit polyclonal antibody
 		905-386

Citations
Launch Citation Database

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