Insulin Receptor Monoclonal Antibody (9H4)

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Description Size Catalog# Price Quantity  
Insulin Receptor Monoclonal Antibody (9H4) 100 µg  905-647 $398.00
Background
The Insulin Receptor (InsR) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. InsR is activated upon binding of the peptide hormone insulin, leading to autophosphorylation of tyrosine residues 1146, 1150, and 1151 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residues 960, 972, 1316, and 1322 regulate the assembly of signal transduction complexes.

Table of Abbreviations

Conjugate

Isotype
IgG1

Product Image(s): click to enlarge

Applications
EIA, IHC, WB

Purification
Thiophilic adsorption and size exclusion chromatography

Immunogen
Synthetic peptide derived from the sequence of Insulin Receptor, conjugated to hemocyanin

Host
Mouse

Clone Number
9H4

Species Reactivity
H, M, R, C

Positive Control
Untreated HepG2 cells

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

Ordering Info
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