IGF-1 Receptor Monoclonal Antibody (7G11)

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Description Size Catalog# Price Quantity  
IGF-1 Receptor Monoclonal Antibody (7G11) 100 µg  905-644 $385.00
Background
Insulin-like growth factor-I (IGF-I) is a polypeptide hormone similar in structure to insulin. It is involved in regulation of neuronal growth and development in the central and peripheral nervous system. IGF-1 is a potent inhibitor of apoptosis in neurons, and activates the Akt signaling pathway via the IGF-1R and Insulin receptors. The IGF-1R acts as a receptor for IGF-1 and the related IGF-2, and is subject to autophosphorylation on multiple tyrosine residues that regulate receptor activation and assembly of signal transduction complexes.

Table of Abbreviations

Abbreviated Name
IGF-1 Receptor mAb (7G11)

Conjugate

Isotype
IgG1

Product Image(s): click to enlarge

Applications
WB

Purification
Thiophilic adsorption and size exclusion chromatography

Immunogen
Synthetic peptide derived from the sequence near the carboxy-terminus of human IGF-1 Receptor, conjugated to hemocyanin

Host
Mouse

Clone Number
7G11

Species Reactivity
H

Positive Control
Untreated A431 cells

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Related Products

Product Name Catalog#
IGF-1 Receptor (phospho-Tyr1316) Monoclonal Antibody (2B9)
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IGF-I (human) EIA Kit
 		900-150
IGF-I Recombinant Human Protein
 		908-059

Citations
Launch Citation Database

Ordering Info
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