CREB (phospho-Ser133) Monoclonal Antibody (10E9)

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Description Size Catalog# Price Quantity  
CREB (phospho-Ser133) Monoclonal Antibody (10E9) 100 µg  905-639 $395.00
Background
The transcription factor CREB (cAMP response element binding) binds the palindromic octanucleotide TGACGTCA. Members of the ATF/CREB family include CREB-1, CREB-2 (also designated ATF-4), ATF-1, ATF-2, and ATF-3. Phosphorylation of CREB allows recruitment of CREB-binding protein (CBP), a large co-activator that contacts the general transcriptional machinery. CREB-mediated transcription regulates diverse cellular responses, including intermediary metabolism, neuronal signaling, cell proliferation, and apoptosis.

Table of Abbreviations

Abbreviated Name
CREB phospho-Ser133 mAb (Ser133)

Conjugate

Isotype
IgG1

Product Image(s): click to enlarge

Applications
EIA, WB

Purification
Thiophilic adsorption and size exclusion chromatography

Immunogen
Synthetic phospho-peptide derived from the sequence of CREB, conjugated to KLH

Host
Mouse

Clone Number
Ser133

Species Reactivity
H, M, C

Positive Control
Pervanadate-treated HepG2 cells

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

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Citations
Launch Citation Database

Ordering Info
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