Chk1 Active Recombinant Protein

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Chk1 Active Recombinant Protein  5 µg PPK-418Z $320.00  
Chk1 Active Recombinant Protein  1 µg PPK-418X $98.00  
Background
The DNA damage checkpoint is a signal transduction pathway that has the ability to delay entry into mitosis. When DNA is damaged, the Check point kinases (CHKs) are known to act downstream of ATM to elicit appropriate responses such as cell cycle arrest. Chk1, for instance, is activated by ATM phosphorylation of serines 123, 178, 278, and 292 of the S phase-promoting cdc25A phosphatase and accelerates IR (ionizing radiation)?induced degradation of cdc25A.

Table of Abbreviations

Species Reactivity
not applicable

Applications
KA

Format
50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol

Purity
>90%

Source
Active recombinant full length human CHK1 containing an N-terminal GST tag, expressed by baculovirus in Sf9 insect cells

For research use only, not for diagnostic or therapeutic use.

Documentation
TechSpec

Product Manual

Product Name Catalog # Manual
Chk1 Active Recombinant Protein PPK-418Z  
Chk1 Active Recombinant Protein PPK-418X  

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Chk1 Monoclonal Antibody (2G1D5)
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Citations
Launch Citation Database

Ordering Info
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