Hsp70 (Hsp72) Active Recombinant Protein

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Hsp70 (Hsp72) Active Recombinant Protein  50 µg SPP-758D $175.00  
Hsp70 (Hsp72) Active Recombinant Protein  200 µg SPP-758F $425.00  
Background
The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

Table of Abbreviations

Species Reactivity
not applicable

Applications
AA, WB Control

Format
Rat Hsp70 in 50mM Tris pH 7.5, 1mM DTT, 100mM NaCl, 0.1mM PMSF.

Product Image(s): click to enlarge

Purity
>90% (SDS-PAGE)

Source
Recombinant rat Hsp70 expressed in E. coli

For research use only, not for diagnostic or therapeutic use.

Documentation
MSDS
TechSpec

Product Manual

Product Name Catalog # Manual
Hsp70 (Hsp72) Active Recombinant Protein SPP-758D  
Hsp70 (Hsp72) Active Recombinant Protein SPP-758F  

Related Products

Product Name Catalog#
Goat anti-Mouse IgG Polyclonal Antibody, AP Conjugate
 		SAB-101J
Hsp70 (Hsp72) Monoclonal Antibody (C92F3A-5)
 		SPA-810
Hsp70 ELISA Kit
 		EKS-700B
PC-12 Cell Lysate (Heat Shocked)
 		LYC-PC101F

Citations
Launch Citation Database

Ordering Info
Click here to learn more about online ordering
 Order by phone: 734-668-6113 or 877-423-4548
Order by e-mail: orders@assaydesigns.com
Order by fax: 734-669-0134