Hsp40 (Hdj1) Recombinant Human Protein

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
Hsp40 (Hdj1) Recombinant Human Protein   50 µg SPP-400D $175.00  
Hsp40 (Hdj1) Recombinant Human Protein   200 µg SPP-400F $430.00  
Background
Hsp40/Hdj1 is a cytosolic co-chaperone belonging to the class DnaJ, named after its homolog in E. coli. Hsp40 functions in protein folding by binding nascent peptides and unfolded substrates and facilitating substrate interaction with Hsp70. Binding of Hsp40 to Hsp70 increases Hsp70 ATP hydrolysis and substrate binding, which is reversed by the action of nucleotide exchange factors (GrpE in E. coli). Repeated cycles of Hsp40/Hsp70 peptide binding and ATP hydrolysis prevent premature folding and aggregation, promoting protein maturation throughout the cell.

Table of Abbreviations

Applications
WB Control

Species Reactivity
Not applicable

Expression System
Recombinant Hsp40 was cloned from a human placenta cDNA library and expressed in E. coli.

Purification
>90 % pure as determined by SDS-PAGE and Western blot analyses

Source
Human

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For research use only, not for diagnostic or therapeutic use.

Documentation
Hsp Luciferase Folding Activity Technical Article
Spec Sheet

Product Manual

Product Name Catalog # Manual
Hsp40 (Hdj1) Recombinant Human Protein SPP-400D  
Hsp40 (Hdj1) Recombinant Human Protein SPP-400F  

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Citations
Launch Citation Database

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